| Characteristic | Description |
|---|---|
| Active Ingredient | Sildenafil |
| Dosage | 50 mg, 100 mg |
| Form | Tablet |
| Administration Route | Oral |
| Discover More | |
Chemical Structure
Sildenafil, known as Viagra Vigour, is a phosphodiesterase type 5 inhibitor. It features a pyrazolopyrimidinone structure with a molecular weight of 474.6 g/mol. Its core consists of a nitrogenous heterocycle, ensuring selective affinity for PDE5. The chemical structure facilitates its specific interaction with enzymatic pathways critical for vasodilation. The presence of methyl and sulfonyl groups in sildenafil enhances solubility and bioavailability, critical factors for its therapeutic efficacy.
In pharmaceutical formulation, sildenafil citrate serves as the active moiety. This salt form improves the compound’s stability and solubility. These attributes enable effective oral absorption. This synthetic compound is optically active and presents as a crystalline powder. It undergoes rigorous quality control measures to ensure consistent potency and safety in clinical use.
Mechanism of Action
Viagra Vigour functions by enhancing nitric oxide effects. It inhibits phosphodiesterase type 5, prevalent in penile tissues. This inhibition prevents the degradation of cyclic guanosine monophosphate (cGMP). Elevated cGMP levels facilitate smooth muscle relaxation and increased blood flow in the corpus cavernosum. This physiological change supports erection in response to sexual stimulation.
Sildenafil’s selective PDE5 inhibition differentiates it from other pharmacological agents. It has minimal effect on PDE6 and PDE1, reducing adverse events related to vision and cardiac function. The peak plasma concentration occurs within 30 to 120 minutes post-administration. A half-life of approximately four hours allows sufficient duration of action with reduced dosing frequency.
Indications
Viagra Vigour is primarily indicated for erectile dysfunction (ED). It is effective in varied patient demographics, including those with underlying conditions such as diabetes or cardiovascular disease. Sildenafil 100 mg provides optimal therapeutic benefit for many patients, enhancing erectile function and satisfaction.
Additional indications include pulmonary arterial hypertension, where sildenafil aids in reducing pulmonary vascular resistance. It enhances exercise capacity and delays disease progression in affected individuals. Off-label uses are explored in specific circulatory disorders, reflecting its potent vasodilatory properties.
Pregnancy and Breastfeeding
Sildenafil is contraindicated during pregnancy due to insufficient safety data. Animal studies reveal potential risks at high doses, but human data remain inconclusive. Its prescription is often avoided unless absolutely necessary.
Breastfeeding mothers should refrain from using Viagra Vigour. The excretion of sildenafil in human milk is unknown, but precaution is advised. Consulting healthcare professionals is crucial before initiating therapy in breastfeeding individuals.
Signs and Symptoms of Overdose
An overdose of Viagra Vigour can provoke severe symptoms. Common signs include dizziness, blurred vision, and chest pain. Uncontrolled blood pressure changes may occur, necessitating immediate medical intervention. Priapism, a prolonged erection, is a critical condition that requires urgent attention.
Management involves symptomatic treatment. Supportive measures include monitoring vital signs and providing oxygen supplementation. Hospitalization may be needed for intravenous fluids and further evaluation.
Viagra Vigour Over The Counter
Viagra Vigour is not available over-the-counter. Prescription is essential due to the need for medical supervision. This ensures appropriate dosing and monitoring of potential interactions.
Purchasing sildenafil from unauthorized sources carries risks. Quality, safety, and authenticity may be compromised. Patients should seek advice from healthcare providers for legitimate options. The therapeutic efficacy and safety of sildenafil remain contingent on professional oversight.
| Viagra Vigour Benefits | Improves erectile function |
|---|---|
| Common Dosages | 50 mg, 100 mg |
| Patient Suitability | Adults with ED |
- Enhances blood flow to the penis
- Selective PDE5 inhibition
- Prolonged efficacy with reduced side effects
For more detailed insights on Viagra Vigour’s pharmacokinetics, visit the PubChem page.
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